The list of aetiological possibilities when it comes to simple splenomegaly is truly massive, but fortunately the list shrinks quite a bit if the spleen attains "massive" status. Sources disagree, but the most commonly-named disorders giving rise to this condition are probably:
- Chronic myeloid leukaemia
- Thalassaemia major or intermedia
- Gaucher's disease
- Tropical splenomegaly
It's quite hard to think of a memory aid for this list. There's lymphoma, one leukaemia, one myeloproliferative disorder, one haemoglobinopathy, one metabolic storage disease, one infection and one idiopathic condition. Any suggestions?