Women have two ovaries, of course, and yet under normal circumstances only one ovum (egg) is released into the abdominal cavity each month. How is this coordinated?
A woman's ova must mature first before they are ready to be released. From birth to puberty, each ovum is surrounded by a single layer of granulosa cells and is termed a primordial follicle. This is more or less how a woman finds her ovaries just before puberty - filled with tens of thousands of primordial follicles.
Each month, some of these follicles are coaxed into further development by the action of two hormones produced in the pituitary gland: luteinizing hormone (LH) and follicle stimulating hormone (FSH). But here's the crucial point: only some of the primordial follicles - typically between six and twelve - develop further each month. These follicles are spread out across both ovaries.
Then, after about a week of stimulation (but before ovulation), one of the follicles begins to outgrow all the others. The others, sensing a winner, give up their chance at immortality and simply involute, leaving the only remaining one to eventually release its ovum. Which ovary (left or right) the winner comes from appears to be largely random - the ovaries aren't so well coordinated as to alternate sides or anything. For instance, the right ovum might produce the ova for three months in a row before the left gets a chance, or vice versa. It's like tossing a coin.
There are two related questions that are begging for an answer here. Firstly, if only one ovum is released each month, why do the other five to eleven of the primary follicles even bother to enter the race? A clue lies in the fact that as follicles develop, they begin to secrete oestrogen and progesterone. Apparently the body needs more than one cell per month in order to generate enough of these hormones - although it obviously needs only a single ovum for fertilisation purposes.
Secondly, what causes the other follicles to give up the race? As the follicles mature, they set up a positive feedback cycle whereby the oestrogen they produce sensitizes the cells to more FSH and LH, which further promotes their development and oestrogen secretion, which sensitizes ... (you get the picture). This process of exponential growth is therefore explosively quick, and so any follicle that edges ahead of the rest of the pack (even if through sheer randomness) quickly outstrips any rivals. It is postulated that this 'dominant follicle' soon secretes so much oestrogen that FSH and LH secretion by the pituitary is suppressed (high levels of oestrogen almost always do this). Starved of stimulation, the paucity of FSH and LH causes the other follicles to involute, whilst the largest follicle is still sufficiently sensitive to the lower levels of FSH and LH to continue its development.
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WhatsApp-(+2348149277967)
Hello everyone, I have been suffering from IC (Interstitial Cystitis) symptoms for 8 months. Never had issues before that, but it came all the sudden and it was HORRIBLE! I was left in absolutely excruciating pain after 4 rounds of antibiotics that I was given to treat the "uti" that I had. I was diagnosed with IC 9 months ago. I've been on the gaps intro diet for a week now. I've been trying to keep my spirits up but I just feel like I'll never feel normal again, because i have being to several hospital for solution but the doctors could not help me, i was discourage and helpless. not until this faithful day, I saw a testimony on how Dr OGBEFUN, helped people in curing Interstitial Cystitis, quickly I copied his Email Dr OGBEFUN, herbal medicine is a good remedy for Interstitial Cystitis, I contacted him and he guided me. I asked him for solutions and he started the remedies for my health he gave me some comforting words with his herbal medicine for curing Interstitial Cystitis within 3weeks of it, i feel my normal body again Thank God now everything is fine, I'm cured by Dr OGBEFUN Herbal medicine, I'm very Thankful to Dr, for curing my Interstitial Cystitis..., kindly contact him today and get your problem solved. Email address,email ogbefunhearlingtemple@gmail.com or add him on whatsapp +2348102574680
ReplyDeleteHe cure listed diseases.
CANCER
HIV/AIDS
HPV
EX BACK
HERPES
HEPATITIS A AND B
DIABETICS
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I am here to give my testimony about Dr latifah who helped me.. i want to inform the public how i was cured from (HERPES SIMPLEX VIRUS) by salami, i visited different hospital but they gave me list of drugs like Famvir, Zovirax, and Valtrex which is very expensive to treat the symptoms and never cured me. I was browsing through the Internet searching for remedy on HERPES and i saw comment of people talking about how Dr latifah cured them. when i contacted him he gave me hope and send a Herbal medicine to me that i took for just 2 weeks and it seriously worked for me, my HERPES result came out negative. I am so happy as i am sharing this testimony. My advice to you all who thinks that there is no cure for herpes that is Not true just contact her and get cure from Dr maam healing herbal cure of all kinds of sickness you may have like
ReplyDelete(1) CANCER,
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I GOT CURED FROM HERPES VIRUS I was diagnosed of HERPES virus and i have tried all I can to get cured but all to no avail,,until I saw a post in a health forum about a herbalist man who prepare herbal medications to cure all kind of diseases including #HERPES virus,at first I doubted if it was real but decided to give it a try,when I contacted this herbalist via his email and he prepared a #HERPES herbal cure and sent it to me via DHL delivery company service, when I received this herbal medicine, he gave me step by direction on how to apply it,after applying the way I was instructed,I was totally cured of this deadly disease called HERPES, all thanks to Dr OGODO Email this great herbal doctor via his email Ogodoherbalhomesolution@gmail.com
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HE CAN ALSO CURE SICKNESS LIKE
{1}HIV/AIDS
{2}DIABETES
{3}EPILEPSY
{4} BLOOD CANCER
{5} HPV
{6} ALS
{7} HEPATITIS
{8}LOVE SPELL
{9} SICKLE AND ANEMIA
Only DR OGODO Can Help You I Love You Father.
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ReplyDelete