Concentration | Major Stimulation | Lifespan | |
Erythrocyte | about 5 x 1012/l | erythropoetin | 120 days |
Leukocyte | 4-11 x 109/l | IL-3, G-CSF, GM-CSF | N = 12 hours, M = months |
Platelet | 150-450 x 109/l | IL-3, IL-6, IL-11, TPO | 4 days |
Key: N = neutrophil, M = monocyte, IL = interleukin, G-CSF = granulocyte colony-stimulating factor, GM-CSF = granulocyte-macrophage colony-stimulating factor, TPO = thrombopoietin
Of note:
- Erythrocytes are by far the most numerous, and they are followed by the platelets and finally the leukocytes. There are about 700 red blood cells to each white blood cell.
- Erythrocytes and monocytes (and lymphocytes, although they're not shown) have relatively long lifespans. Not so for the platelets or the neutrophils. If the latter isn't activated, it lasts just hours. (And even an activated one is viable for only slightly longer.)
- Lastly, a complete list of all the stimulating factors for all the cells is ludicrously long and complicated. I've only concentrated on the major ones for each major cell line.
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