In terms of acid-base balance, aldosterone stimulates a pump in the kidney (technically, on the intercalated cells of the collecting duct) that normally pushes out H+ ions into the urine. In other words, under normal circumstances this pump has the effect of causing H+ loss by the body, making it more alkaline (higher pH).
From this it's easy to work out what happens in aldosterone hyposecretion: the pump is understimulated, resulting in H+ retention and acidosis. (It's usually mild, however.)
Aldosterone also has some interesting effects on other electrolytes - sodium and potassium in particular - but we'll have to cover that on some other occassion.
We are indeed wonderfully, created!
ReplyDeleteThanks for the information.
Keep your sodium intake under control makes good health, Aldactone prevents your body from absorbing too much salt & keeps your potassium levels from getting too low.
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