Friday, 25 April 2008

What is the likely effect of aldosterone hyposecretion on body pH?

In terms of acid-base balance, aldosterone stimulates a pump in the kidney (technically, on the intercalated cells of the collecting duct) that normally pushes out H+ ions into the urine. In other words, under normal circumstances this pump has the effect of causing H+ loss by the body, making it more alkaline (higher pH).

From this it's easy to work out what happens in aldosterone hyposecretion: the pump is understimulated, resulting in H+ retention and acidosis. (It's usually mild, however.)

Aldosterone also has some interesting effects on other electrolytes - sodium and potassium in particular - but we'll have to cover that on some other occassion.

2 comments:

  1. We are indeed wonderfully, created!
    Thanks for the information.

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  2. Keep your sodium intake under control makes good health, Aldactone prevents your body from absorbing too much salt & keeps your potassium levels from getting too low.

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